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Date: 27 November 2006 - 17:30
Speaker: Sir Michael J. Berridge, Laboratory of Molecular Signalling, The Babraham Institute, Cambridge
Venue: The Royal Society of Edinburgh
Cells have access to a very extensive Ca2+ signalling toolkit from which each cell type expresses a unique set of components to create Ca2+ signalling systems with different spatial and temporal properties. Such signalling systems are constantly being remodelled. A number of important disease states may result from abnormal remodelling of Ca2+ signalling systems. Congestive heart failure, a major cause of human morbidity and mortality, is controlled by a number of signalling pathways of which Ca2+ seems to play a prominent role.
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