Improving health through research

Starter Grants for Clinical Lecturers

These grants provide up to £30,000 over 1-2 years for consumables, to support Clinical Lecturers who are looking to develop and strengthen their research careers.

Key dates

Round 11 is now closed. The next round will open in July.

Starter Grants for Clinical Lecturers offer funding of up to £30,000 to cover the cost of research consumables. The grants allow research-active Clinical Lecturers to gather data to strengthen their bids for longer-term fellowships and funding.

About the scheme

This scheme was scheme was launched in October 2008 as a partnership between the Academy and the Wellcome Trust, and we were delighted to welcome the British Heart Foundation in 2011 and Arthritis Research UK in 2012. In 2013, the Medical Research Council joined the consortium as a major funder, and Prostate Cancer UK brought the total number of funders up to five. In 2014 we warmly welcome our most recent funder to the consortium, the Royal College of Physicians.

The grants provide modest ‘starter’ funds to enable research active Clinical Lecturers to pursue their research work. Clinical Lecturer posts provide a salary but often do not come with the funding to support the costs of the research. This scheme was designed to help bridge this gap by providing Clinical Lecturers with access to modest research funds for up to two years. It gives them experience of preparing a research grant application and helps them establish their research portfolios by providing funding for research consumables.

So far we have supported 194 Clinical Lecturers through nine rounds of funding, with grants totalling nearly £5.5 million. In 2011, the Academy and the Wellcome Trust carried out a review of the scheme, which you can download from the right hand side of this page.

In December 2013, we launched the Winter Science Meeting for Starter Grant Holders, an annual event organised exclusively for Starter Grant Holders. For more information please visit the main Winter Science Meeting page.

To be eligible to apply you must:

  • Be a research-active Clinical Lecturer and hold an NTN or NTN(A).
  • Have a PhD or MD.
  • Hold a medical or dental undergraduate degree and be registered with the General Medical Council or General Dental Council.
  • Be within higher specialty training.

Clinical Lectureships in Primary Care are awarded post-CCT and we welcome applications from this group.However, for all other specialties, you are not eligible to apply if you have already attained your CCT, and at least half of your proposed research must fall before your planned CCT. Senior Clinical Lecturers, Clinical Psychologists and Vets are not eligible for this scheme.

If you have qualified abroad with an MD you should have undertaken a substantial period of research equivalent to a PhD or research MD.

Please download the application guidelines for full details of the eligibility for this scheme.

This scheme is targeted at those who are in the earlier years of their Clinical Lecturer appointment. You should not already have obtained substantial funding from other sources, for example a Clinician Scientist Fellowship, New Investigator Award or large project grant.

The maximum grant available is £30,000. This can be spread over one to two years to contribute towards directly incurred research costs such as consumables and equipment.

Grants cannot be used to pay for your personal salary costs or to support research assistants, PhD students or postdoctoral staff.

Successful applicants cannot reapply. Unsuccessful applicants are limited to one resubmission.

The current members of the selection panel are:

Professor Marina Botto FMedSci (chair), Imperial College London

Professor Wiebke Arlt FMedSci, University of Birmingham

Professor Patrick Chinnery FMedSci, Newcastle University

Professor Hilary Critchley FRSE FMedSci, University of Edinburgh

Professor David Edwards FMedSci, King's College London

Professor Michael Frenneaux FMedSci, University of Aberdeen

Professor Freddie Hamdy FMedSci, University of Oxford

Professor Jonathan Shepherd CBE FMedSci FLSW, University of Cardiff (from round 12)

Professor Ros Smyth FMedSci, University College London

 

Applicants should not approach Panel members to discuss their application. All queries should be directed to the Panel secretariat on clinicallecturers@acmedsci.ac.uk.

All Starter Grant Holders are required to report via Researchfish annually by the end of March each year. Click here for full reporting instructions.

You will also need to submit (email to clinicallecturers@acmedsci.ac.uk) a Final Expenditure Report within 3 months of the end of your grant in addition to submitting Researchfish data. You can download the final expenditure form from the right hand side of this page.

Awardees

Dr Tomoki Arichi, King's College London: Exploration of the neuronal underpinnings of the haemodynamic response to stimulation in the neonatal brain using simultaneous EEG-fMRI

Dr Simon Bomken, Newcastle University: Pre-clinical modelling and functional analysis of childhood Burkitt lymphoma

Dr Sam Chamberlain, University of Cambridge: Dopaminergic modulation of cognition in adults with Attention-Deficit Hyperactivity Disorder (ADHD)

Dr Krishna Dani, University of Glasgow: Pilot MRI Study for the Investigation of Pathophysiology of Intra-cerebral Haemorrhage

Dr Thushan de Silva, University of Sheffield: Exploring novel mechanisms of vaccine failure and induction of pulmonary immunity following live attenuated influenza vaccination in HIV-infected individuals: a pilot study

Dr Michael Devine, University of Cambridge: Using single-molecule imaging of beta-amyloid to study pathogenic mechanisms and improve diagnostics of Alzheimer’s disease

Dr Christopher Gale, Imperial College London: Simplified neonatal nutrition clinical trials using electronic health records: a feasibility and pilot study

Dr Paolo Gallipoli, University of Cambridge: Investigation of the role of the CBP and p300 lysine acetyltransferases in the maintenance of Acute Myeloid Leukaemia

Dr Debra Josephs, King’s College London: Novel mechanistic insights into the macrophage-activating functions of a tumour antigen-specific IgE antibody for cancer immunotherapy

Dr Alan Karthikesalingam, St George's University London: An Ambulance Scoring System for Prehospital Diagnosis and Triage of Ruptured Aortic Aneurysm

Dr Rajeev Krishnadas, University of Glasgow: Exploring the impact of peripheral immune challenge on the “triple network” and “Dorsal nexus” functional connectivity in humans

Dr Lei Liu, University of Bristol: Regulation of angiogenesis through cytosine-phosphate-guanosine oligodeoxynucleotide (CpG ODN)

Dr Konstantinos Manolopoulos, University of Birmingham: Glucocorticoid-dependent regulation of adipose tissue thermogenesis and oxidative metabolism

Dr Jacqueline McDermott, Queen Mary University of London: Cancer stem cells and chemokines in high grade serous adenocarcinoma

Dr Tanya Monaghan, University of Nottingham: Investigation of the effect of lactoferrin in an in vitro human gut model predictive of Clostridium difficile infection

Dr Rajarshi Mukherjee, University of Liverpool: Mitochondrial signalling pathways in the pathogenesis of acute necrotising pancreatitis

Mr Daniel Perry, University of Warwick: Investigating the UK epidemiology of slipped capital femoral epiphysis: A population based descriptive and case-control study

Dr Bethan Psaila, Imperial College London: The Role of Megakaryocytes in Myeloproliferative Disorders

Dr Simon Rinaldi, University of Oxford: An examination of membrane associated heteromeric complexes as ligands for neuropathy associated antibodies

Dr Patricia Roxburgh, University of Glasgow: The relationship between p53 mutation, inflammation and survival in high-grade serous ovarian cancer

Dr Manish Sadarangani, University of Oxford: Using gene expression analysis to rationally design future vaccines, by investigation of the immune response to the novel meningococcal vaccine MenPF in a phase I trial.

Dr Victoria Salem, Imperial College London: Evaluation of a novel positron emission tomography (PET) tracer for the direct measurement of brown adipose tissue (BAT) thermogenesis

Dr Katherine Sleeman, King’s College London: Emergency Department attendance amongst patients with advanced dementia in England, 2011-2012

Dr Adam Smith-Collins, University of Bristol: Novel imaging biomarkers of potential brain injury and altered development in preterm infants    

Dr Bas Van Rijn, University of Southampton: Circulating MicroRNAs as Biomarkers to Predict Pregnancy Outcome

Dr Liaquat Verjee, University of Oxford: Role of IL-33 in driving local inflammation in Dupuytren’s disease

Dr Ruben Willemsen, University of Cambridge: The effect of neonatal IGF-1 levels in preterm babies on long-term beta cell function

Dr Caroline Williams-Gray, University of Cambridge: The role of inflammation in the dementia of Parkinson’s disease

Dr Guilherme Xavier, King’s College London: Understanding the genetics of eruption failure and supernumerary tooth formation in cleidocranial dysplasia

Dr Timothy Yap, Institute of Cancer Research: Genomic changes in plasma DNA reflect tumoural mutations in advanced KRAS-mutant lung adenocarcinoma and can be utilized to guide patient treatment

Dr Aminul Ahmed, University of Southampton: Regulation of neural stem cells in acute and chronic injury

Dr Claire Booth,University College London: Targeted gene addition strategies for the treatment of X-linked lymphoproliferative disease (XLP)

Dr Rachel Clough, King’s College London: An integrated imaging and modelling approach for individualised treatment planning in aortic dissection

Dr Laura Coates, University of Leeds: Investigating the phenotype of axial psoriatic arthritis

Dr Mark Gilchrist, University of Exeter: Determination of endogenous nitrate synthesis rate in haemodialysis patients using a novel stable isotope method

Dr Nigel Jamieson, University of Glasgow: NcRNA biomarkers in pancreaticobiliary malignancy - implications for therapy

Dr James Lee, University of Cambridge: FOXO3 and the regulation of inflammatory responses – implications for inflammatory and infectious disease

Dr George Mells, University of Cambridge: Investigation of the genetic basis of disease progression in primary biliary cirrhosis

Dr Andrew Monk, University of Oxford: Evolutionary morphological considerations in orthopaedic surgery

Dr Helen Petersen, University College London: Orofacial granulomatosis; a disorder of the innate immune response

Dr Thomas Smith, University of Oxford: Preliminary study of hypoxic conditioning in the elderly

Dr Mkael Symmonds, University of Oxford: Measuring synaptic function using electroencephalography and magnetoencephalography

Dr Lucy Walker, University of Newcastle: The role of CD8aa expressing T-cells in hepatitis B infection

Dr James Ware, Imperial College London: Identification of genes and pathways underlying dilated cardiomyopathy

Dr Brian Wilson, University of Newcastle: Developing tissue-specific models of the premature ageing distorder, Cockayne syndrome, using patient-derived human induced pluripotent stem cells

Dr Peter Yeates, University of Manchester: Investigating the influence of assessors’ stereotypical beliefs relating to students’ gender or ethnicity on performance judgements in medical education

Dr Danilo Arnone, King's College London: Evaluation of amygdala neural responses as a putative distinctive biomarker for bipolar disorder vs. unipolar depression

Dr Mona Bafadhel, University of Leicester: Investigating the mechanism of eosinophil activity in COPD phenotypes

Dr Anita Balakrishnan, University of Cambridge: The role of impaired acetaldehyde metabolism in pancreatic carcinogenesis

Dr Andrew Beggs, University of Birmingham: Molecular analysis of determinants of radiosensitivity and recurrence in rectal tumours

Dr Hannah Durrington, University of Manchester: IRAK1-a novel target for REV-ERBα? The role of the circadian clock in the immune system

Dr Andrew Fry, Cardiff University: What is the genetic basis of familial polymicrogyria?

Dr James Galea, University of Manchester: The role of haemoglobin in neuronal inflammation and cell death

Dr Madeleine Hewish, Institute of Cancer Research: Exploration of the relationships between oxidative stress, cell adhesion, resistance to anoikis and selected molecular aberrations in colorectal cancer

Dr Syed Ali Khurram, University of Sheffield: Epithelial-fibroblast cross-talk in metastatic intranodal oral squamous cell carcinoma- Is it the hallmark of aggressive disease?

Dr James Kinross, Imperial College London: Chemically augmented imaging of gut microbiome / host interactions in colorectal cancer

Dr Christian Lambert, University of London: Developing high-resolution individual-level computational functional neuroanatomy for translational applications in diagnostic neuroimaging and functional neurosurgery

Dr Verity McClelland, King's College London: Corticomuscular coherence in childhood dystonia

Dr Neal Millar, University of Glasgow: The role of mast cells in the pathogenesis of tendon disease

Dr Rachel Myles, University of Glasgow: Mechanisms of early afterdepolarisations in the long QT syndrome: a study of cellular voltage and calcium dynamics in the intact heart

Dr Fu Siong Ng, Imperial College London: The role of the Purkinje-myocardial junction in ventricular arrhythmogenesis

Dr Rajan Patel, University of Glasgow: Effect of cool temperature haemodialysis on myocardial metabolic function

Dr Shelley Potter, Bristol University: The development of a core outcome set for research and audit in reconstructive breast surgery

Dr Oliver Rider, University of Oxford: Effect of obesity on myocardial metabolism using hyperpolarized C13 imaging

Dr Stuart Smith, University of Birmingham: Stromal cell function in the pathogenesis of renal fibrosis

Dr Katy Vincent, University of Oxford: Identifying predictors and correlates of the response to surgical treatment of endometriosis-related pain

Dr Ed Vital, University of Leeds: Understanding cutaneous responses to rituximab in systemic lupus erythematosus

Dr Catriona Waitt, University of Liverpool: Development and validation of an assay for quantitation of antiretrovirals in human breastmilk

Dr Sarah Zaher, University College London: Identification of therapeutic targets for acute corneal graft rejection

Dr Thomas Bird, University of Edinburgh: Observation of the differentiation of hepatic stem cells into hepatocytes in real time

Dr Elizabeth Bird-Lieberman, University of Cambridge: Molecular imaging of glycosylation changes in Barrett’s oesophagus to detect dysplasia: endoscopic and radiological applications

Dr John Blaikley, University of Manchester: The role of macrophage lipid metabolism in pulmonary fibrosis

Dr Patrick Calvert, University of Cambridge: Metabolic and anatomical assessment of coronary artery plaque vulnerability

Dr Louise Coats, University of Newcastle: A 4D flow sensitive magnetic resonance study of patent foramen ovale in cryptogenic stroke

Dr Federico Foschi, King's College London: When to stop? Determine the endpoint of root canal treatment by spectrophotometric measurement of bacterial fluorescence

Dr Refik Gökmen, King's College London: Defining the role of T-bet in regulatory T cell function

Dr Nigel Hall, University College London: Identification of novel biomarkers of intestinal ischaemia in infants

Dr David Hunt, University of Edinburgh: How does abnormal nucleic acid processing trigger neuroinflammation?

Dr Marko Kerac, University College London: Community management of acute malnutrition in infants aged <6 months (CMAMI): formative research toward a future RCT

Dr Matthew Krebs, University of Manchester: Molecular characterisation of circulating tumour cells

Dr Mariya Moosajee, University College London: Non viral gene therapy for Ushers Syndrome

Dr Abhik Mukherjee, University of Nottingham: Early phase metastatic behaviour in breast cancer: Standardisation of detection methodology for lymphovascular invasion (LVI) and molecular characterisation of the LVI positive phenotype

Dr Nirupa Murugaesu, University College London: Defining drivers of metastatic progression by deciphering intratumour heterogeneity and bottlenecking events in squamous non-small cell lung carcinoma

Dr Christopher Neal, University of Leicester: The Nek2 mitotic kinase in pancreatic carcinogenesis

Dr Rupert Payne, University of Cambridge: Evaluating the impact of unsafe prescribing in primary care

Dr Jacqueline Phillips Owen, King's College London: Addressing psychiatric comorbidity in children with epilepsy in rural Kenya

Dr David Porter, University of Oxford: The effect of BCG on serogroup C meningococcal immunisation in UK infants

Dr Arthur Pratt, University of Newcastle: Understanding the pathobiology of seronegative inflammatory arthritis: routes to stratified medicine

Dr Tamir Rashid, University of Cambridge: Advancing hIPSC derived hepatocyte disease models

Dr Adam Reid, University of Manchester: Adipose-derived stem cells for peripheral nerve repair

Dr Charlotte Summers, University of Cambridge: Mechanism and role of neutrophil de-priming in vitro and in vivo

Dr David Thomas, University of Cambridge: A gene essential for the control of salmonella typhimurium

Dr Nick West, University of Leeds: Understanding the response to chemotherapy in colon cancer: patterns of cell death and DNA damage

Dr Trevor Yeung, University of Oxford: Colorectal cancer stem cells and their microenvironment: clinical implications in metastatic lymph nodes

Supporters

We are grateful for substantial funding for this scheme from the Wellcome Trust and the Medical Research Council.

Wellcome Trust

Medical Research Council

The scheme is also generously supported by the British Heart Foundation, Arthritis Research UK, Prostate Cancer UK and the Royal College of Physicians.

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